Alright, so I’ve been messing around with different bot lane combos in League of Legends, and today I wanna talk about Pyke, that bloodthirsty support, and who’s best to pair him up with. I spent a good chunk of time trying out different ADCs with Pyke, and boy, did I learn a lot.
First off, I dove into some online guides and tier lists. They kept mentioning names like Seraphine, Karthus, Tristana, and Jinx. So, naturally, I started there. The idea was to see which of these ADCs could really make the most of Pyke’s aggressive playstyle.

Trying Out Different Combos
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Seraphine: I kicked things off with Seraphine. The guides said she was good, but honestly, it felt a bit clunky. Her abilities are great for poke and sustain, but when it came to all-in fights, which Pyke loves, it didn’t quite click. We had some decent moments, but it wasn’t the power duo I was hoping for.
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Karthus: Next up was Karthus. This one was interesting. His ability to deal damage from afar with his Q and his ultimate did help soften up targets for Pyke to finish off. But, Karthus is squishy, and if we got caught out, it was game over. It was a high-risk, high-reward kind of situation. We won some, we lost some, it was a mixed bag really.
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Tristana: Then I moved on to Tristana. Now, this was more like it. Her explosive charge paired with Pyke’s hooks and stuns made for some nasty burst damage. We could delete an enemy ADC in seconds. Plus, her jump gave her an escape if things got hairy. We started winning more consistently with this combo.
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Jinx: Last but not least, I tried Jinx. And let me tell you, this was the jackpot. Jinx’s long-range rockets and traps synergized perfectly with Pyke’s kit. He could hook someone in, and Jinx could follow up with her chompers and rockets. We dominated the lane more often than not. It felt like we were always one step ahead of the enemy.
After all that testing, if I had to pick the best ADC to run with Pyke, it’s gotta be Jinx. They just work so well together. Pyke’s crowd control sets up Jinx to deal massive damage, and they both have that killer instinct. But, Tristana is a close second. Her burst and mobility make her a solid choice too.
So, that’s my take on the best ADC with Pyke. It took some trial and error, but hey, that’s how you learn. If you’re a Pyke main or just looking to spice up your bot lane, give Jinx or Tristana a shot. You might just find your new favorite duo.